Comparative Effectiveness Research

Comparative Effectiveness Research PDF
Author: Carol M. Ashton
Publisher: Oxford University Press
ISBN: 019996856X
Size: 10.89 MB
Format: PDF, Kindle
Category : Medical
Languages : en
Pages : 290
View: 6890

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Comparative Effectiveness Research

by Carol M. Ashton, Comparative Effectiveness Research Books available in PDF, EPUB, Mobi Format. Download Comparative Effectiveness Research books, Comparative Effectiveness Research: Evidence, Medicine, and Policy provides the first complete account of how — and why — the federal government decided to make comparative effectiveness research (CER) an important feature of health reform and the Affordable Care Act of 2010.


Methods In Comparative Effectiveness Research

Methods in Comparative Effectiveness Research PDF
Author: Constantine Gatsonis
Publisher: CRC Press
ISBN: 1466511974
Size: 75.83 MB
Format: PDF, Mobi
Category : Mathematics
Languages : en
Pages : 554
View: 2351

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Methods In Comparative Effectiveness Research

by Constantine Gatsonis, Methods In Comparative Effectiveness Research Books available in PDF, EPUB, Mobi Format. Download Methods In Comparative Effectiveness Research books, Comparative effectiveness research (CER) is the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical condition or to improve the delivery of care (IOM 2009). CER is conducted to develop evidence that will aid patients, clinicians, purchasers, and health policy makers in making informed decisions at both the individual and population levels. CER encompasses a very broad range of types of studies—experimental, observational, prospective, retrospective, and research synthesis. This volume covers the main areas of quantitative methodology for the design and analysis of CER studies. The volume has four major sections—causal inference; clinical trials; research synthesis; and specialized topics. The audience includes CER methodologists, quantitative-trained researchers interested in CER, and graduate students in statistics, epidemiology, and health services and outcomes research. The book assumes a masters-level course in regression analysis and familiarity with clinical research.


Comparative Effectiveness Research

Comparative Effectiveness Research PDF
Author: Francesco Chiappelli
Publisher:
ISBN: 9781634843157
Size: 21.97 MB
Format: PDF
Category :
Languages : en
Pages : 558
View: 5956

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Comparative Effectiveness Research

by Francesco Chiappelli, Comparative Effectiveness Research Books available in PDF, EPUB, Mobi Format. Download Comparative Effectiveness Research books, Briefly stated, comparative effectiveness research pertains to the direct, succinct and precise comparison of existing healthcare interventions to determine what works best for each individual patient, and which treatment course poses the greatest benefits, costs and harms. The core question of comparative effectiveness research goes beyond establishing what treatment works best, for whom, and under what circumstances: it is a hypothesis-driven endeavor designed to uncover and implement the consensus of the best evidence base for patient-centered, effectiveness-focused and evidence-based health care. Members at the Institute of Medicine and the Patient-Centered Outcomes Research concur that comparative effectiveness research involves the generation and synthesis of the best available evidence for a treatment intervention by means of a process driven by the PICOTS question/hypothesis, and are directed at comparing and contrasting the benefits, costs and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical conditions with the specified intent of improving the delivery of health care. The purpose of comparative effectiveness research is to assist healthcare providers, patients, allied clinicians, caregivers and other stakeholders to engage together and make informed decisions that will improve healthcare at both the individual and population levels, and in so doing utilize the identified best evidence base in specific clinical settings, a process that the Agency for Healthcare Research and Quality defines as "Translational Effectiveness". In brief, comparative effectiveness research is the tool and the process necessary for translational effectiveness. In this light, it is critical and timely to facilitate comparative effectiveness research as one of the essential and primary components of patient-centered, effectiveness-focused and evidence-based clinical decision-making in healthcare, as the premier process that results in improved patient outcomes, enhanced research planning, better products, and novel evidence-based policy development. This book is a compilation of the writings of several experts in the field and their collaborators. Each chapter examines specific facets of the process of comparative effectiveness research-based clinical decision-making in the principal domains of healthcare, which are subsumed in this work as dentistry, Western and alternative medicine, nursing, and pharmacology. Taken together, the chapters in this book present a brief, yet comprehensive overview and discussion of the current state of comparative effectiveness in healthcare. They establish the central role of systematic reviews in the process of clinical decision-making in evidence-based health care, and examine in depth the statistical significance and the clinical relevance of actualizing and evaluating clinical decision-making. Additionally, policies in optimizing evidence-based, patient-centered and effectiveness-focused clinical outcomes, stakeholders engagement for raising health literacy in the U.S. and worldwide in this decade of the twenty-first century and beyond are discussed.


Decision Making In A World Of Comparative Effectiveness Research

Decision Making in a World of Comparative Effectiveness Research PDF
Author: Howard G. Birnbaum
Publisher: Springer
ISBN: 9811032629
Size: 61.75 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 289
View: 3312

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Decision Making In A World Of Comparative Effectiveness Research

by Howard G. Birnbaum, Decision Making In A World Of Comparative Effectiveness Research Books available in PDF, EPUB, Mobi Format. Download Decision Making In A World Of Comparative Effectiveness Research books, In the past decade there has been a worldwide evolution in evidence-based medicine that focuses on real-world Comparative Effectiveness Research (CER) to compare the effects of one medical treatment versus another in real world settings. While most of this burgeoning literature has focused on research findings, data and methods, Howard Birnbaum and Paul Greenberg (both of Analysis Group) have edited a book that provides a practical guide to decision making using the results of analysis and interpretation of CER. Decision Making in a World of Comparative Effectiveness contains chapters by senior industry executives, key opinion leaders, accomplished researchers, and leading attorneys involved in resolving disputes in the life sciences industry. The book is aimed at 'users' and 'decision makers' involved in the life sciences industry rather than those doing the actual research. This book appeals to those who commission CER within the life sciences industry (pharmaceutical, biologic, and device manufacturers), government (both public and private payers), as well as decision makers of all levels, both in the US and globally.


Initial National Priorities For Comparative Effectiveness Research

Initial National Priorities for Comparative Effectiveness Research PDF
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309138361
Size: 71.32 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 252
View: 4387

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Initial National Priorities For Comparative Effectiveness Research

by Institute of Medicine, Initial National Priorities For Comparative Effectiveness Research Books available in PDF, EPUB, Mobi Format. Download Initial National Priorities For Comparative Effectiveness Research books, Clinical research presents health care providers with information on the natural history and clinical presentations of disease as well as diagnostic and treatment options. In today's healthcare system, patients, physicians, clinicians and family caregivers often lack the sufficient scientific data and evidence they need to determine the best course of treatment for the patients' medical conditions. Initial National Priorities for Comparative Effectiveness Research(CER) is designed to fill this knowledge gap by assisting patients and healthcare providers across diverse settings in making more informed decisions. In this 2009 report, the Institute of Medicine's Committee on Comparative Effectiveness Research Prioritization establishes a working definition of CER, develops a priority list of research topics, and identifies the necessary requirements to support a robust and sustainable CER enterprise. As part of the 2009 American Recovery and Reinvestment Act, Congress appropriated $1.1 billion in federal support of CER, reflecting legislators' belief that better decisions about the use of health care could improve the public's health and reduce the cost of care. The Committee on Comparative Effectiveness Research Prioritization was successful in preparing a list 100 top priority CER topics and 10 recommendations for best practices in the field.


Comparative Effectiveness Research In Oncology

Comparative Effectiveness Research in Oncology PDF
Author:
Publisher:
ISBN:
Size: 50.40 MB
Format: PDF, Docs
Category :
Languages : en
Pages :
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Comparative Effectiveness Research In Oncology

by , Comparative Effectiveness Research In Oncology Books available in PDF, EPUB, Mobi Format. Download Comparative Effectiveness Research In Oncology books, Learning Objectives: Describe methods for assessing comparative effectiveness in the absence of data from high‐quality randomized, controlled trials. Outline the criteria that should be applied to systematic reviews in order to use them for comparative effectiveness research. Abstract : Although randomized controlled trials represent the gold standard for comparative effective research (CER), a number of additional methods are available when randomized controlled trials are lacking or inconclusive because of the limitations of such trials. In addition to more relevant, efficient, and generalizable trials, there is a need for additional approaches utilizing rigorous methodology while fully recognizing their inherent limitations. CER is an important construct for defining and summarizing evidence on effectiveness and safety and comparing the value of competing strategies so that patients, providers, and policymakers can be offered appropriate recommendations for optimal patient care. Nevertheless, methodological as well as political and social challenges for CER remain. CER requires constant and sophisticated methodological oversight of study design and analysis similar to that required for randomized trials to reduce the potential for bias. At the same time, if appropriately conducted, CER offers an opportunity to identify the most effective and safe approach to patient care. Despite rising and unsustainable increases in health care costs, an even greater challenge to the implementation of CER arises from the social and political environment questioning the very motives and goals of CER. Oncologists and oncology professional societies are uniquely positioned to provide informed clinical and methodological expertise to steer the appropriate application of CER toward critical discussions related to health care costs, cost‐effectiveness, and the comparative value of the available options for appropriate care of patients with cancer. Abstract : Randomized controlled trials represent the gold standard for comparative effective research, but additional methods are available when randomized controlled trials are lacking or inconclusive. Comparative effective research requires oversight of study design and analysis, but if appropriately conducted, offers an opportunity to identify the most effective and safe approach to patient care. Oncologists and oncology societies are uniquely positioned to provide the expertise to steer the appropriate application of comparative effective research.


Comparative Effectiveness Research In Heart Failure An Issue Of Heart Failure Clinics

Comparative Effectiveness Research in Heart Failure  An Issue of Heart Failure Clinics  PDF
Author: Mark Hlatky
Publisher: Elsevier Health Sciences
ISBN: 1455771856
Size: 38.76 MB
Format: PDF, ePub, Mobi
Category : Medical
Languages : en
Pages : 120
View: 6303

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Comparative Effectiveness Research In Heart Failure An Issue Of Heart Failure Clinics

by Mark Hlatky, Comparative Effectiveness Research In Heart Failure An Issue Of Heart Failure Clinics Books available in PDF, EPUB, Mobi Format. Download Comparative Effectiveness Research In Heart Failure An Issue Of Heart Failure Clinics books, This issue of Heart Failure Clinics covers comparative-effectiveness research in heart failure. Expert authors review the most current information available about the comparative effectiveness of different treatments for heart failure, including drug treatments, cardioverter defibrillators and cardiac resynchronization therapy, as well as patient adherence. Keep up-to-the-minute with the latest developments in comparative-effectiveness research.


How Will Comparative Effectiveness Research Affect The Quality Of Health Care

How Will Comparative Effectiveness Research Affect the Quality of Health Care  PDF
Author: Elizabeth Docteur
Publisher:
ISBN:
Size: 72.94 MB
Format: PDF, ePub, Docs
Category :
Languages : en
Pages :
View: 2127

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How Will Comparative Effectiveness Research Affect The Quality Of Health Care

by Elizabeth Docteur, How Will Comparative Effectiveness Research Affect The Quality Of Health Care Books available in PDF, EPUB, Mobi Format. Download How Will Comparative Effectiveness Research Affect The Quality Of Health Care books,