Mucosal Delivery Of Drugs And Biologics In Nanoparticles

Mucosal Delivery of Drugs and Biologics in Nanoparticles PDF
Author: Pavan Muttil
Publisher: Springer Nature
ISBN: 3030359107
Size: 18.52 MB
Format: PDF
Category : Medical
Languages : en
Pages : 277
View: 839

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Mucosal Delivery Of Drugs And Biologics In Nanoparticles

by Pavan Muttil, Mucosal Delivery Of Drugs And Biologics In Nanoparticles Books available in PDF, EPUB, Mobi Format. Download Mucosal Delivery Of Drugs And Biologics In Nanoparticles books, Nanotechnology has revolutionized the approach to designing and developing novel drug delivery systems. The last two decades have seen a great interest in the use of nanotechnology to offer efficient ways of delivering new and existing drugs and macromolecules. The focus of this book is the application of nanotechnology to deliver drugs and biological agents by the mucosal routes of administration i.e. nasal, pulmonary, buccal, and oral routes. It provides an overview of nanotechnology in drug delivery with a description of different types of nanoparticles, methods of preparation and characterization, and functionalization for site-specific drug delivery. The emphasis is on the use of nanoparticles in treating various cancers and infectious diseases. It broadens the use of nanoparticles by including biologics, including vaccines and immunotherapies, apart from drugs and acknowledges the concerns around the potential toxicity of nanoparticles to the host; several chapters will discuss the biodistribution of these nanoparticles when mucosal routes of administration are employed. Further, the interaction of nanoparticles with the host’s immune cells is discussed. Moreover, it reviews the regulatory aspects of nanotechnology in product development, especially when delivered by the mucosal route of administration. Lastly, discusses the challenges and opportunities to manufacture nanoparticles on an industrial scale. This book is the first of its kind to focus on the design, development and delivery of nanoparticles when administered by different mucosal routes.


Nanotechnology Based Approaches For Targeting And Delivery Of Drugs And Genes

Nanotechnology Based Approaches for Targeting and Delivery of Drugs and Genes PDF
Author: Vijay Mishra
Publisher: Academic Press
ISBN: 0128097183
Size: 63.59 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 552
View: 7610

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Nanotechnology Based Approaches For Targeting And Delivery Of Drugs And Genes

by Vijay Mishra, Nanotechnology Based Approaches For Targeting And Delivery Of Drugs And Genes Books available in PDF, EPUB, Mobi Format. Download Nanotechnology Based Approaches For Targeting And Delivery Of Drugs And Genes books, Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes provides an overview of the important aspects of nanomedicine in order to illustrate how to design and develop novel and effective drug delivery systems using nanotechnology. The book is organized into three sections, beginning with an introduction to nanomedicine and its associated issues. Section two discusses the latest technologies in nanomedicine, while the third section covers future developments and challenges in the field. By focusing on the design, synthesis, and application of a variety of nanocarriers in drug and gene delivery, this book provides pharmaceutical and materials science students, professors, clinical researchers, and industry scientists with a valuable resource aimed at tackling the challenges of delivering drugs and genes in a more targeted manner. Explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advances in cutting-edge nanomedical technologies Contains contributions from world-renowned experts and researchers working in the area of nanomedicine and drug delivery Covers the associated challenges and potential solutions to working with nanotechnology in drug delivery Highlights crucial topics, such as biopharmaceutical and toxicity issues, quality by design, drug targeting, and more


Drug Efficacy Safety And Biologics Discovery

Drug Efficacy  Safety  and Biologics Discovery PDF
Author: Sean Ekins
Publisher: John Wiley & Sons
ISBN: 0470431806
Size: 23.63 MB
Format: PDF
Category : Medical
Languages : en
Pages : 400
View: 7337

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Drug Efficacy Safety And Biologics Discovery

by Sean Ekins, Drug Efficacy Safety And Biologics Discovery Books available in PDF, EPUB, Mobi Format. Download Drug Efficacy Safety And Biologics Discovery books, Drug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools covers key emerging technologies in pharmaceutical R & D and how they have substantially impacted (or are currently impacting) drug discovery. The cross-disciplinary collaborations implicit in integrating these technologies with drug discovery operations will fuel the engine for future innovations. This book cuts across the multiple areas of drug discovery, each chapter authored by pioneers in that field, making for a broad appeal to the chemical and biological scientists and technologists involved in drug discovery and development.


Mucosal Delivery Of Biopharmaceuticals

Mucosal Delivery of Biopharmaceuticals PDF
Author: José das Neves
Publisher: Springer Science & Business Media
ISBN: 1461495245
Size: 19.96 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 601
View: 965

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Mucosal Delivery Of Biopharmaceuticals

by José das Neves, Mucosal Delivery Of Biopharmaceuticals Books available in PDF, EPUB, Mobi Format. Download Mucosal Delivery Of Biopharmaceuticals books, Biopharmaceutical medicines, the newest class of therapeutics, are quite heterogeneous and include a range of molecules such as proteins, peptides, vaccines and nucleic acids, with use in virtually all therapeutic fields (e.g. cancer and infectious diseases, vaccination, metabolic dysfunctions) and diagnostics. This edited book gives a concise and up-to-date overview of the biological features justifying the use of different human mucosa as delivery routes for biopharmaceuticals, the technological strategies that have been followed so far regarding the optimization of mucosal potentialities as well as the challenges that arise with the advent of new biopharmaceutical drugs and alternative means of administration. Following a brief introduction, the first section addresses general aspects of the biology of mucosal tissues and their unique aspects toward beneficial or deleterious interaction with biopharmaceuticals and their delivery systems. The second part reviews the different delivery strategies that have recently been investigated for different mucosal sites. The third section describes the development and clinical applications of drug delivery systems and products enclosing biopharmaceuticals for mucosal delivery, with a focus on the most successful case studies of recent years. The last section briefly centers on relevant aspects of the regulatory, toxicological and market issues of mucosal delivery of biopharmaceuticals.​ Scientists and researchers in the fields of drug delivery, material science, biomedical science and bioengineering as well as professionals, regulators and policy makers in the pharmaceutical, biotechnology and healthcare industries will find in this book an important compendium of fundamental concepts and practical tools for their daily research and activities.


Nanotechnology For Oral Drug Delivery

Nanotechnology for Oral Drug Delivery PDF
Author: João Pedro Martins
Publisher: Academic Press
ISBN: 0128180390
Size: 65.32 MB
Format: PDF, ePub
Category : Business & Economics
Languages : en
Pages : 534
View: 4826

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Nanotechnology For Oral Drug Delivery

by João Pedro Martins, Nanotechnology For Oral Drug Delivery Books available in PDF, EPUB, Mobi Format. Download Nanotechnology For Oral Drug Delivery books, Nanotechnology for Oral Drug Delivery: From Concept to Applications discusses the current challenges of oral drug delivery, broadly revising the different physicochemical barriers faced by nanotechnolgy-based oral drug delivery systems, and highlighting the challenges of improving intestinal permeability and drug absorption. Oral delivery is the most widely used form of drug administration due to ease of ingestion, cost effectiveness, and versatility, by allowing for the accommodation of different types of drugs, having the highest patient compliance. In this book, a comprehensive overview of the most promising and up-to-date engineered and surface functionalized drug carrier systems, as well as opportunities for the development of novel and robust delivery platforms for oral drug administration are discussed. The relevance of controlling the physicochemical properties of the developed particle formulations, from size and shape to drug release profile are broadly reviewed. Advances in both in vitro and in vivo scenarios are discussed, focusing on the possibilities to study the biological-material interface. The industrial perspective on the production of nanotechnology-based oral drug delivery systems is also covered. Nanotechnology for Oral Drug Delivery: From Concept to Applications is essential reading for researchers, professors, advanced students and industry professionals working in the development, manufacturing and/or commercialization of nanotechnology-based systems for oral drug delivery, targeted drug delivery, controlled drug release, materials science and biomaterials, in vitro and in vivo testing of potential oral drug delivery technologies. Highlights the relevance of oral drug delivery in the clinical setting Covers the most recent advances in the field of nanotechnology for oral drug delivery Provides the scientific community with data that can facilitate and guide their research


Pediatric Allergy Principles And Practice E Book

Pediatric Allergy  Principles and Practice E Book PDF
Author: Donald Y. M. Leung
Publisher: Elsevier Health Sciences
ISBN: 1437737781
Size: 45.75 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 704
View: 5081

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Pediatric Allergy Principles And Practice E Book

by Donald Y. M. Leung, Pediatric Allergy Principles And Practice E Book Books available in PDF, EPUB, Mobi Format. Download Pediatric Allergy Principles And Practice E Book books, Pediatric Allergy supplies the comprehensive guidance you need to diagnose, manage, and treat virtually any type of allergy seen in children. Drs. Leung, Sampson, Geha, and Szefler present the new full-color second edition, with coverage of the diagnosis and management of anaphylaxis, the immune mechanisms underlying allergic disease, the latest diagnostic tests, and more. Treat the full range of pediatric allergic and immunologic diseases through clinically focused coverage relevant to both allergists and pediatricians. Understand the care and treatment of pediatric patients thanks to clinical pearls discussing the best approaches. Easily refer to appendices that list common food allergies and autoantibodies in autoimmune diseases. Apply the newest diagnostic tests available—for asthma, upper respiratory allergy, and more—and know their benefits and contraindications. Treat the allergy at its source rather than the resulting reactions through an understanding of the immune mechanisms underlying allergic diseases. Get coverage of new research that affects methods of patient treatment and discusses potential reasons for increased allergies in some individuals. Better manage potential anaphylaxis cases through analysis of contributing facts and progression of allergic disease. Effectively control asthma and monitor its progression using the new step-by-step approach. Eliminate difficulty in prescribing antibiotics thanks to coverage of drug allergies and cross-reactivity.


Handbook Of Pharmaceutical Biotechnology

Handbook of Pharmaceutical Biotechnology PDF
Author: Shayne C. Gad
Publisher: Wiley-Interscience
ISBN:
Size: 63.44 MB
Format: PDF
Category : Medical
Languages : en
Pages : 1659
View: 6222

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Handbook Of Pharmaceutical Biotechnology

by Shayne C. Gad, Handbook Of Pharmaceutical Biotechnology Books available in PDF, EPUB, Mobi Format. Download Handbook Of Pharmaceutical Biotechnology books, Describes the use of biotechnology to develop pharmaceuticals. This book gives the professional a basic tool to facilitate the development of biotech medicines by bringing together a general overview of biotechnology used in the drug development process, along with a compendium of regulations and validation methods.


Applied Biopharmaceutics Pharmacokinetics Sixth Edition

Applied Biopharmaceutics   Pharmacokinetics  Sixth Edition PDF
Author: Leon Shargel
Publisher: McGraw Hill Professional
ISBN: 0071603948
Size: 22.96 MB
Format: PDF, Kindle
Category : Medical
Languages : en
Pages : 811
View: 1886

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Applied Biopharmaceutics Pharmacokinetics Sixth Edition

by Leon Shargel, Applied Biopharmaceutics Pharmacokinetics Sixth Edition Books available in PDF, EPUB, Mobi Format. Download Applied Biopharmaceutics Pharmacokinetics Sixth Edition books, A comprehensive textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics The field’s leading text for more than three decades Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition provides you with a basic understanding of the principles of biopharmaceutics and pharmacokinetics and applies these principles to drug product development, drug product performance and drug therapy. The revised and updated sixth edition is unique in teaching basic concepts that relate to understanding the complex issues associated with safe and efficacious drug therapy. Written by authors who have both academic and clinical experience, Applied Biopharmaceutics & Pharmacokinetics will help you to: Understand the basic concepts in biopharmaceutics and pharmacokinetics. Use raw data and derive the pharmacokinetic models and parameters that best describe the process of drug absorption, distribution, and elimination Critically evaluate biopharmaceutic studies involving drug product equivalency and unequivalency Design and evaluate dosage regimens of drugs, using pharmacokinetic and biopharmaceutic parameters Detect potential clinical pharmacokinetic problems and apply basic pharmacokinetic principles to solve them Practical problems and clinical examples with discussions are included in each chapter to help you apply these principles to patient care and drug consultation situations. Chapter Objectives, Chapter Summaries, and Frequently Asked Questions along with additional application questions appear within each chapter to identify and focus on key concepts. Most of the chapters have been revised to reflect our current understanding of drug product performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy.