Neuronal Inputs And Outputs Of Aging And Longevity

Neuronal Inputs and Outputs of Aging and Longevity PDF
Author: Joy Alcedo
Publisher: Frontiers
ISBN: 2889191605
Size: 23.21 MB
Format: PDF
Category :
Languages : en
Pages :
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Neuronal Inputs And Outputs Of Aging And Longevity

by Joy Alcedo, Neuronal Inputs And Outputs Of Aging And Longevity Books available in PDF, EPUB, Mobi Format. Download Neuronal Inputs And Outputs Of Aging And Longevity books, An animal’s survival strongly depends on its ability to maintain homeostasis in response to the changing quality of its external and internal environments. This is achieved through intercellular communication not only within a single tissue but also among different tissues and organ systems. Thus, alterations in tissue-to-tissue or organ-to-organ communications, which are under genetic regulation, can affect organismal homeostasis, and consequently impact the aging process. One of the organ systems that play a major role in maintaining homeostasis is the nervous system. Considering that the nervous system includes the sensory system, which perceives the complexity of an animal’s environment, it should be no surprise that there would be a sensory influence on homeostasis and aging. To promote homeostasis, any given sensory information is transmitted through short-range signals via neural circuits and/or through long-range endocrine signals to target tissues, which may in turn be neuronal or non-neuronal in nature. At the same time, since homeostasis involves a number of feedback mechanisms, non-neuronal tissues can also modulate sensory and other neuronal functions. Several genes that regulate signaling pathways known to affect homeostasis and aging have been shown to act in neurons, in tissues that are likely downstream targets of the nervous system, or through feedback regulation of neuronal activities. These genes can have different temporal requirements: some might function early, e.g., by affecting neural development, while others may only be required later in adulthood. Some well-known examples of genes involved in the neuronal regulation of homeostasis and longevity encode components of the evolutionarily conserved nutrient-sensing insulin/insulin-like signaling pathway, the stress-sensing internal repair system, and the mitochondrial electron transport chain. Indeed, the genetic perturbation of these pathways has been found to lead to numerous diseases, many of which are age-related and involve the nervous system, such as neurodegeneration and the metabolic syndrome. Despite much progress, however, many aspects of the neuronal inputs and outputs that affect aging and longevity are poorly understood to date. For example, the precise neuronal and non-neuronal circuitries and the details of the molecular mechanisms through which genes/signaling pathways maintain homeostasis and affect aging in response to the environment remain to be elucidated. Similarly, it is presently unclear whether genes that regulate the early development of the nervous system and its consequent circuitry influence homeostasis and longevity during adulthood. At the same time, although many genes affecting aging are conserved, both the nervous system and the aging process are highly variable within populations and among taxa. Accordingly, the role of natural genetic variation in shaping the neurobiology of aging is also presently unknown. The aim of this Research Topic is therefore to highlight the genetic, developmental, and physiological aspects of the signaling networks that mediate the neuronal inputs and outputs that are required to maintain organismal homeostasis. The elucidation of the effects of these neuronal activities on homeostasis may thus provide much-needed insight into mechanisms that affect aging and longevity.


Life Span Motor Development

Life Span Motor Development PDF
Author: Kathleen Haywood
Publisher: Human Kinetics Publishers
ISBN: 149256690X
Size: 23.19 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 448
View: 4151

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Life Span Motor Development

by Kathleen Haywood, Life Span Motor Development Books available in PDF, EPUB, Mobi Format. Download Life Span Motor Development books, Life Span Motor Development, Seventh Edition, uses the model of constraints in discussing reasons for changes in movement throughout the life span. It encourages students to examine how the interactions of the individual, environment, and task bring about changes in a person's movements.


Neurological Research Supported By The National Institute Of Neurological Diseases And Stroke

Neurological Research Supported by the National Institute of Neurological Diseases and Stroke PDF
Author: National Institute of Neurological Diseases and Stroke
Publisher:
ISBN:
Size: 14.25 MB
Format: PDF
Category : Neurology
Languages : en
Pages : 256
View: 6771

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Neurological Research Supported By The National Institute Of Neurological Diseases And Stroke

by National Institute of Neurological Diseases and Stroke, Neurological Research Supported By The National Institute Of Neurological Diseases And Stroke Books available in PDF, EPUB, Mobi Format. Download Neurological Research Supported By The National Institute Of Neurological Diseases And Stroke books,


Neurobiology Of Aging

Neurobiology of Aging PDF
Author: J. Ordy
Publisher: Springer
ISBN: 9780306379161
Size: 23.70 MB
Format: PDF, ePub, Docs
Category : Medical
Languages : en
Pages : 603
View: 1014

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Neurobiology Of Aging

by J. Ordy, Neurobiology Of Aging Books available in PDF, EPUB, Mobi Format. Download Neurobiology Of Aging books, Aging is one of the most universal and inevitable social and sci entific challenges confronting man. The lives of all multicellular organisms begin with conception, extend through phases of development, maturity, senescence and finally end in death. Man is no exception, but has the unique feature of a complex brain. It plays an integra tive role in adaptation to the physical and social environments through reflexes, conditioning and more complex forms of learning. The brain is a repository for both inherited and acquired information. With the development of speech and the formation of symbolic language, the human brain has made it possible to transmit information cultur ally (horizontal) to other members of society, in addition to genetic (vertical) transmission to progeny. This horizontal transmission, which has reached its highest form in man, is a powerful extension of genetic transmission. The brain may provide man all that is of im portance in life. It has played a key role in the evolution of life by maintaining and extending the life span. Many mental or intellectual capacities of man reach a peak in early adulthood, remain relatively constant throughout maturity and then appear to decline during senescence. Behaviorally, there appears to be a decrease in sensory, learning and motor functions with aging in all mammalian species. As integrated adaptive control systems, the brain and neuroendocrines have been closely associated with the homeostatic adaptation to environmental challenges throughout .the life span.


Handbook Of Mental Health And Aging

Handbook of Mental Health and Aging PDF
Author: James E. Birren
Publisher: Academic Press
ISBN:
Size: 41.56 MB
Format: PDF, ePub
Category : Health & Fitness
Languages : en
Pages : 996
View: 7031

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Handbook Of Mental Health And Aging

by James E. Birren, Handbook Of Mental Health And Aging Books available in PDF, EPUB, Mobi Format. Download Handbook Of Mental Health And Aging books, This book is a thorough revision of one of the most comprehensive reference volumes for persons working in the area of aging and mental health. The thrust of the work is interdisciplinary, and discusses research on both clinical and practical issues in aging and mental health. The multidisciplinary nature of this book and the inclusion of subject matter from the professional as well as research realm result in a level of comprehensiveness which is distinct in the field of mental health and aging Each chapter contains a comprehensive bibliography, the compilation of which represents a definitive reference source in the field The chapters review state-of-the-art research in the biological, behavioral, and social sciences and represent the cutting-edge of current practice in psychiatry, neurology, social work, nursing, psychology, and pharmacology, among other professions The compilation of prevalence data is a much-needed addition to the current literature The multidisciplinary nature of this book and the inclusion of both clinical and practical issues makes the book distinctively comprehensive


Handbook Of Developmental Psychology

Handbook of Developmental Psychology PDF
Author: Benjamin B. Wolman
Publisher: Prentice Hall
ISBN: 9780133725995
Size: 80.97 MB
Format: PDF, ePub, Docs
Category : Psychology
Languages : en
Pages : 960
View: 6309

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Handbook Of Developmental Psychology

by Benjamin B. Wolman, Handbook Of Developmental Psychology Books available in PDF, EPUB, Mobi Format. Download Handbook Of Developmental Psychology books,


Medinfo 2019 Health And Wellbeing E Networks For All

MEDINFO 2019  Health and Wellbeing e Networks for All PDF
Author: L. Ohno-Machado
Publisher: IOS Press
ISBN: 164368003X
Size: 37.90 MB
Format: PDF, Kindle
Category : Medical
Languages : en
Pages : 2076
View: 3303

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Medinfo 2019 Health And Wellbeing E Networks For All

by L. Ohno-Machado, Medinfo 2019 Health And Wellbeing E Networks For All Books available in PDF, EPUB, Mobi Format. Download Medinfo 2019 Health And Wellbeing E Networks For All books, Combining and integrating cross-institutional data remains a challenge for both researchers and those involved in patient care. Patient-generated data can contribute precious information to healthcare professionals by enabling monitoring under normal life conditions and also helping patients play a more active role in their own care. This book presents the proceedings of MEDINFO 2019, the 17th World Congress on Medical and Health Informatics, held in Lyon, France, from 25 to 30 August 2019. The theme of this year’s conference was ‘Health and Wellbeing: E-Networks for All’, stressing the increasing importance of networks in healthcare on the one hand, and the patient-centered perspective on the other. Over 1100 manuscripts were submitted to the conference and, after a thorough review process by at least three reviewers and assessment by a scientific program committee member, 285 papers and 296 posters were accepted, together with 47 podium abstracts, 7 demonstrations, 45 panels, 21 workshops and 9 tutorials. All accepted paper and poster contributions are included in these proceedings. The papers are grouped under four thematic tracks: interpreting health and biomedical data, supporting care delivery, enabling precision medicine and public health, and the human element in medical informatics. The posters are divided into the same four groups. The book presents an overview of state-of-the-art informatics projects from multiple regions of the world; it will be of interest to anyone working in the field of medical informatics.


Development Of Eye Hand Coordination Across The Life Span

Development of Eye hand Coordination Across the Life Span PDF
Author: Chantal Bard
Publisher:
ISBN:
Size: 36.80 MB
Format: PDF, Kindle
Category : Psychology
Languages : en
Pages : 384
View: 1858

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Development Of Eye Hand Coordination Across The Life Span

by Chantal Bard, Development Of Eye Hand Coordination Across The Life Span Books available in PDF, EPUB, Mobi Format. Download Development Of Eye Hand Coordination Across The Life Span books, A comprehensive treatment of eye-hand coordination and how it changes as a function of age. Topics include the latest in theory, research, and practice, more specifically the environmental and genetic contributions to eye-hand coordination, basic neurophysiological processes, object manipulation and


Index Medicus

Index Medicus PDF
Author:
Publisher:
ISBN:
Size: 19.91 MB
Format: PDF, Kindle
Category : Medicine
Languages : en
Pages :
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Index Medicus

by , Index Medicus Books available in PDF, EPUB, Mobi Format. Download Index Medicus books,


Handbook Of Biological Psychiatry

Handbook of Biological Psychiatry PDF
Author: Herman Meïr Praag
Publisher:
ISBN:
Size: 73.18 MB
Format: PDF, ePub, Docs
Category : Mental illness
Languages : en
Pages :
View: 942

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Handbook Of Biological Psychiatry

by Herman Meïr Praag, Handbook Of Biological Psychiatry Books available in PDF, EPUB, Mobi Format. Download Handbook Of Biological Psychiatry books,